Oneself antibody and nature abort
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In a lot of natural abortion, through medical personnel long-term research discovers, positive of certain oneself antibody leads heighten in serum, also be to relapse natural abortion woman's common immunology unusual element. These are unusual, basically be with fight lecithin antibody, fight thyroid antibody to wait have affinity.
Fighting lecithin antibody is to be aimed at all sorts of floorboard of a variety of antibody that take antigen of electronegative charge phosphatide, among them, in clinical getting on two the most important kinds with research is lupus fight coagulate content and antibody of the lecithin that fight a heart, weigh latter as the generation that fights phosphatide antibody.
Medicine considers to make clear, in 50%- - the iteration of 60% aborts naturally in the patient, often can see fight lecithin antibody, and in normal crowd, its occurence rate is occupied merely 4% . Abroad has an expert to think, fighting lecithin antibody is not action at gravid and inchoate bring about abortion, is action merely at gravid metaphase, terminal, make fetal death. Accordingly, fighting lecithin antibody may be medium the element of terminal abortion, if be in the patient of terminal abortion, hormone of medicaments of cure of applied needle sex or anti-coagulants therapy effect are very distinct, gravid and successful rate is 70% ; And the patient that produces inchoate abortion treats the effect not apparent, gravid and successful rate is only 35% .
Investigator fights lecithin antibody positive to abort naturally repeatedly through the examination placental discovery of the patient, what its embryo take inventory accumulates in bedding face is necrotic, speculation fights lecithin antibody to bring about abort naturally repeatedly the apparent mechanism that happen may be fit and alimentary layer forms interference placenta, can pass block up prostate the way such as the generation of annulus element, bring about agglomeration of the plaque inside placenta, thrombosis and placental embolism, and bring about abortion.
Accordingly, already the scholar thinks to lecithin antibody is fought inside body of Yo age woman unusual the dangerous mark of obstacle of reproduction be consideringed as. In recent years, still a few study the result makes clear, repeatedly natural abortion and fight thyroid antibody to concern. Abroad has investigator discovery, in the woman that aborts naturally repeatedly, the generation that fights thyroid antibody is led relatively antibody of oneself of blame organ particularity is tall, the person that fight thyroid antibody positive again the dangerous sex of gravid abortion is more electronegative person apparent also heighten.
Besides, abroad still has investigator report, the woman that aborts naturally repeatedly fights thyroid antibody positive to lead apparent prep above to contrast normally group, but reproduction assists technical woman and do not have difference with experience, because this thinks to fight the mark that thyroid antibody may be oneself immunity activation, increase with the dangerous sex that produces abortion and postpartum thyroid disease relevant. In addition, foreign investigator confirms, fight thyroid antibody to divide with abort naturally repeatedly outside concerning, still concern with stillborn foetus and preeclampsia.
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